10. Lou Gehrig’s patients begin to have problems with their body’s handling of proteins.
When nerve cells do not process proteins well, they may gather proteins. This can lead to the death of nerve cells. In most cases, nerve cells repair damage using protein. In patients with ALS however, nerve cells cannot process proteins properly.
The patient’s mental limit begins to show up as nerve cells die due to an inappropriate protein mix. Psychological wellness may continue to decline. Memory loss may also be a sign. The nerves continue to separate, which causes electrical signals to be lost to the extremities and farthest points. This results in the slurring and death associated with Lou Gehrig’s Disease.
Protein Degradation Pathway has been responsible for improving ALS symptoms in people affected. This pathway is similar to the one used by patients with Parkinson’s disease and Alzheimer’s.
